[1]李小勇.纤维支气管镜吸痰灌洗治疗重症监护室肺部感染的效果[J].医学信息,2021,34(23):147-149.[doi:10.3969/j.issn.1006-1959.2021.23.044]
　LI Xiao-yong.Effect of Fiberoptic Bronchoscopy Alveolar Lavage in the Treatment of Pulmonary Infection in Intensive Care Unit[J].Medical Information,2021,34(23):147-149.[doi:10.3969/j.issn.1006-1959.2021.23.044]
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纤维支气管镜吸痰灌洗治疗重症监护室肺部感染的效果()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年23期
页码:
147-149
栏目:
临床研究
出版日期:
2021-12-01

文章信息/Info

Title:
Effect of Fiberoptic Bronchoscopy Alveolar Lavage in the Treatment of Pulmonary Infection in Intensive Care Unit
文章编号:
1006-1959（2021）23-0147-03
作者:
李小勇
（上犹县人民医院呼吸与危重症医学科，江西 上犹 341200）
Author(s):
LI Xiao-yong
(Department of Respiratory and Critical Care Medicine,Shangyou County People’s Hospital,Shangyou 341200,Jiangxi,China)
关键词:
重症监护室; 肺部感染; 纤维支气管镜吸痰灌洗
Keywords:
Intensive care unit; Pulmonary infection; Fiberoptic bronchoscopy alveolar lavage
分类号:
R563.1
DOI:
10.3969/j.issn.1006-1959.2021.23.044
文献标志码:
A
摘要:
目的 研究纤维支气管镜吸痰灌洗治疗重症监护室（ICU）肺部感染的临床效果。方法 选取2020年3月-2021年3月我院ICU收治的80例肺部感染患者作为研究对象，按照随机数字表法分为对照组与观察组，各40例。对照组行常规基础治疗，观察组在对照组基础上行纤维支气管镜吸痰灌洗治疗，比较两组治疗前后血气指标[动脉血氧分压（PaO2）、动脉血二氧化碳分压（PaCO2）、动脉血氧饱和度（SaO2）]、血清炎症因子[干扰素1（IFN-γ）、白细胞介素-2（IL-2）、白细胞介素-13（IL-13）]、血清应激指标[皮质醇（Cor）、肾上腺素（ADR）、去甲肾上腺素（NADR）]、不良反应发生情况。结果 观察组PaO2、SaO2高于对照组，PaCO2低于对照组，差异有统计学意义（P＜0.05）；观察组IFN-γ、IL-2低于对照组，IL-13高于对照组，差异有统计学意义（P＜0.05）；观察组血清Cor、ADR、NADR含量低于对照组，差异有统计学意义（P＜0.05）；观察组不良反应发生率为5.00%，低于对照组的20.00%，差异有统计学意义（P＜0.05）。结论 纤维支气管镜吸痰灌洗治疗可有效改善ICU肺部感染患者的血氧状态，缓解机体炎性反应与应激状态，降低不良反应发生风险。
Abstract:
Objective To study the clinical effect of fiberoptic bronchoscopy alveolar lavage in the treatment of pulmonary infection in intensive care unit (ICU).Methods A total of 80 patients with pulmonary infection admitted to ICU of our hospital from March 2020 to March 2021 were selected as the research objects. According to the random number method, they were divided into control group and observation group, with 40 cases in each group. The control group was treated with routine basic treatment, and the observation group was treated with fiberoptic bronchoscopy alveolar lavage on the basis of the control group. The blood gas indexes [arterial partial pressure of oxygen (PaO2), arterial partial pressure of carbon dioxide (PaCO2), arterial oxygen saturation (SaO2)], serum inflammatory factors [interferon 1 (IFN-γ), interleukin-2 (IL-2), interleukin-13 (IL-13)], serum stress indexes [cortisol (Cor), adrenaline (ADR), norepinephrine (NADR)] and adverse reactions were compared between the two groups before and after treatment.Results The levels of PaO2 and SaO2 in the observation group were higher than those in the control group, PaCO2 was lower than that in the control group, the difference was statistically significant (P<0.05). The levels of IFN-γ and IL-2 in the observation group were lower than those in the control group, and IL-13 was higher than that in the control group, the difference was statistically significant (P<0.05). The levels of Cor, ADR and NADR in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). The incidence of adverse reactions in the observation group was 5.00%, which was lower than 20.00% in the control group, and the difference was statistically significant (P<0.05).Conclusion Fiberoptic bronchoscopy alveolar lavage can effectively improve the blood oxygen status of ICU patients with pulmonary infection, alleviate the inflammatory response and stress state of the body, and reduce the risk of adverse reactions.

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更新日期/Last Update: 1900-01-01