[1]杨丽红,肖 波,侯丽霞,等.淫羊藿苷调节细胞增殖作用的研究进展[J].医学信息,2019,32(01):33-36.[doi:10.3969/j.issn.1006-1959.2019.01.012]
 YANG Li-hong,XIAO Bo,HOU Li-xia,et al.Advances in Research on the Regulation of Cell Proliferation by Icariin[J].Journal of Medical Information,2019,32(01):33-36.[doi:10.3969/j.issn.1006-1959.2019.01.012]
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淫羊藿苷调节细胞增殖作用的研究进展()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年01期
页码:
33-36
栏目:
综述
出版日期:
2019-01-01

文章信息/Info

Title:
Advances in Research on the Regulation of Cell Proliferation by Icariin
文章编号:
1006-1959(2019)01-0033-04
作者:
杨丽红肖 波侯丽霞姚 冬
桂林医学院附属医院呼吸内科,广西 桂林 541004
Author(s):
YANG Li-hongXIAO BoHOU Li-xiaYAO Dong
Department of Respiratory Medicine,Affiliated Hospital of Guilin Medical College,Guilin 541004,Guangxi,China
关键词:
淫羊藿苷细胞增殖促进抑制
Keywords:
IcariinCell proliferationPromotionInhibition
分类号:
R285.6
DOI:
10.3969/j.issn.1006-1959.2019.01.012
文献标志码:
A
摘要:
淫羊藿苷是传统补益中药淫羊藿的有效活性成分之一,研究发现可影响多种细胞的增殖。淫羊藿苷主要促进骨组织相关细胞增殖,包括成骨细胞、软骨细胞、骨膜细胞、间充质干细胞,淫羊藿苷抑制多种肿瘤细胞增殖,包括骨肉瘤细胞、乳腺癌细胞和卵巢癌细胞等,淫羊藿苷亦可调节其他细胞的增殖,包括神经干细胞、平滑肌细胞等。但淫羊藿苷对细胞增殖促进和抑制的双重调节机制需要进一步研究,方能为其在细胞增殖紊乱相关疾病中的应用提供理论依据。
Abstract:
Icariin is one of the effective active ingredients of traditional Chinese herbal medicine Epimedium, which has been found to affect the proliferation of various cells. Icariin mainly promotes the proliferation of bone-related cells, including osteoblasts, chondrocytes, periosteal cells, mesenchymal stem cells, and icariin inhibits proliferation of various tumor cells, including osteosarcoma cells, breast cancer cells, and ovarian cancer. Apoptosis can also regulate the proliferation of other cells, including neural stem cells and smooth muscle cells. However, the dual regulation mechanism of icariin on cell proliferation promotion and inhibition needs further research to provide a theoretical basis for its application in cell proliferation disorders.

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更新日期/Last Update: 2019-01-22