[1]金 川,张 颖,李瑞环,等.葛根芩连汤对2型糖尿病患者糖脂代谢指标及 体重的影响[J].医学信息,2019,32(14):164-165.[doi:10.3969/j.issn.1006-1959.2019.14.055]
　JIN Chuan,ZHANG Ying,LI Rui-huan,et al.Effect of Gegen Qinlian Decoction on Glucose and Lipid Metabolism Index and Body Weight in Patients with Type 2 Diabetes Mellitus[J].Journal of Medical Information,2019,32(14):164-165.[doi:10.3969/j.issn.1006-1959.2019.14.055]
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葛根芩连汤对2型糖尿病患者糖脂代谢指标及 体重的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年14期
页码:
164-165
栏目:
中医中药
出版日期:
2019-07-15

文章信息/Info

Title:
Effect of Gegen Qinlian Decoction on Glucose and Lipid Metabolism Index and Body Weight in Patients with Type 2 Diabetes Mellitus
文章编号:
1006-1959（2019）14-0164-02
作者:
金 川; 张 颖; 李瑞环; 刘保兵
天津市滨海新区大港医院中医科，天津 300270
Author(s):
JIN Chuan; ZHANG Ying; LI Rui-huan; LIU Bao-bing
Department of Traditional Chinese Medicine,Dagang Hospital,Binhai New Area,Tianjin 300270, China
关键词:
2型糖尿病; 葛根芩连汤; 二甲双胍; 糖脂代谢指标; 体重
Keywords:
Key words：Type 2 diabetes mellitus; Gegen Qilian decoction; Metformin; Glycolipid metabolism index;  Body weight
分类号:
R587.1
DOI:
10.3969/j.issn.1006-1959.2019.14.055
文献标志码:
A
摘要:
目的 探究葛根芩连汤对对2型糖尿病患者糖脂代谢指标及体重的影响。方法 选取2017年1月~2019年1月我院收治的2型糖尿病患者60例，采用随机数字表法分为对照组和观察组，各30例。对照组给予口服盐酸二甲双胍片治疗，观察组在对照组基础上联合葛根芩连汤治疗。对比两组治疗前后糖脂代谢指标、体重变化及不良反应发生率。结果 治疗后观察组FPG（6.21±0.74）mmol/L、HbAlc（6.23±0.45）%、TC（3.75±0.52）mmol/L、TG（1.76±0.35）mmol/L、LDL-C（3.03±0.44）mmol/L及BMI指数（24.13±1.82）kg/m2，分别低于对照组的（7.26±0.83）mmol/L、（7.49±0.58）%、（4.88±0.56）mmol/L、（2.62±0.41）mmol/L、（3.69±0.48）mmol/L、（26.56±1.71）kg/m2，差异有统计学意义(P＜0.05)；观察组HDL-C（1.55±0.20）mmol/L，高于对照组的（1.36±0.15）mmol/L，差异有统计学意义(P＜0.05)；观察组不良反应发生率为6.67%，低于对照组的16.67%，但差异无统计学意义（P＞0.05）。结论 葛根芩连汤治疗有助于更好的改善糖脂代谢各指标水平，控制患者体重，且药物安全性高，利于预后恢复。
Abstract:
Abstract：Objective To investigate the effect of Gegen Qinlian Decoction on glucose and lipid metabolism and body weight in patients with type 2 diabetes mellitus. Methods 60 patients with type 2 diabetes admitted to our hospital from January 2017 to January 2019 were enrolled. The patients were randomly divided into the control group and the observation group, 30 cases each. The control group was treated with oral metformin hydrochloride tablets, and the observation group was treated with Gegen Qinlian Decoction on the basis of the control group. The glucose and lipid metabolism indicators, body weight changes and incidence of adverse reactions were compared before and after treatment. Results After treatment, FPG (6.21±0.74) mmol/L, HbAlc (6.23±0.45)%, TC (3.75±0.52) mmol/L, TG (1.76±0.35) mmol/L, LDL-C (3.03±0.44) mmol/L and BMI index (24.13±1.82) kg/m2 were lower than those of the control group (7.26±0.83) mmol/L, (7.49±0.58)%, (4.88±0.56) mmol/L, (2.62±0.41) mmol/L, (3.69±0.48) mmol/L, (26.56±1.71) kg/m2, the difference was statistically significant (P<0.05);the observation group HDL -C(1.55±0.20) mmol/L was higher than that of the control group (1.36±0.15) mmol/L, the difference was statistically significant (P<0.05); the incidence of adverse reactions in the observation group was 6.67%, which was lower than that of the control group 16.67%, but the difference was not statistically significant (P>0.05).Conclusion Gegen Qinlian Decoction can improve the level of glucose and lipid metabolism, control the body weight of patients, and the safety of the drug is high, which is conducive to the recovery of prognosis.

参考文献/References:

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更新日期/Last Update: 2019-07-15