[1]于占妹.2型糖尿病下肢血管病变的危险因素分析[J].医学信息,2020,33(18):101-103.[doi:10.3969/j.issn.1006-1959.2020.18.033]
　YU Zhan-mei.Risk Factors of Lower Extremity Vascular Disease in Type 2 Diabetes Mellitus[J].Medical Information,2020,33(18):101-103.[doi:10.3969/j.issn.1006-1959.2020.18.033]
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2型糖尿病下肢血管病变的危险因素分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年18期
页码:
101-103
栏目:
临床研究
出版日期:
2020-09-15

文章信息/Info

Title:
Risk Factors of Lower Extremity Vascular Disease in Type 2 Diabetes Mellitus
文章编号:
1006-1959（2020）18-0101-03
作者:
于占妹
（天津市宁河区宁河医院内科，天津 301500）
Author(s):
YU Zhan-mei
(Department of Medicine,Ninghe Hospital,Ninghe District,Tianjin 301500,China)
关键词:
2型糖尿病; 下肢血管病变; 蛋白尿
Keywords:
Type 2 diabetes; Lower extremity vascular disease; Proteinuria
分类号:
R587.1
DOI:
10.3969/j.issn.1006-1959.2020.18.033
文献标志码:
A
摘要:
目的 了解2型糖尿病下肢动脉病变病例特点及危险因素。方法 收集2018年1月~2019年12月天津市宁河区某医院体检的150例糖尿病患者的体检资料，依据踝/肱动脉比值（ABI）将患者分为糖尿病下肢血管病变（DLEV组）和糖尿病非下肢血管病变（非DLEV组），分析两组一般资料情况，并采用多因素Logsitic分析糖尿病下肢动脉病变的影响因素。结果 共150例糖尿病患者，其中存在糖尿病下肢血管病变者35例。两组年龄、性别、血脂水平比较，差异无统计学意义（P＞0.05）；两组病程、BMI、吸烟史、饮酒史、空腹血糖、糖化血红蛋白、血压、蛋白尿比较，差异有统计学意义（P＜0.05）；多因素Logistic分析显示，病程、空腹血糖、血压水平、蛋白尿等是糖尿病足下肢动脉病变的危险因素。结论 糖尿病足下肢血管病变患者多糖尿病病程较长，空腹血糖、血压控制不佳，多兼有蛋白尿等情况。临床中应对以上因素予以重视，以控制和改善糖尿病下肢血管病变的发生、发展。
Abstract:
Objective To understand the characteristics and risk factors of lower extremity arterial disease in type 2 diabetes.Methods The physical examination data of 150 diabetic patients who were examined in a hospital in Ninghe District, Tianjin from January 2018 to December 2019 were collected, and the patients were divided into diabetic lower extremity vascular disease (DLEV group) and based on the ankle/brachial artery ratio (ABI). Diabetic non-lower extremity vascular disease (non-DLEV group), analyze the general data of the two groups, and use multivariate Logsitic to analyze the influencing factors of diabetic lower extremity arterial disease.Results A total of 150 patients with diabetes, including 35 patients with diabetic lower limb vascular disease. There was no statistically significant difference between the two groups in age, gender, and blood lipid levels (P>0.05); the two groups had statistically significant differences in the course of disease, BMI, smoking history, drinking history, fasting blood glucose, glycosylated hemoglobin, blood pressure, and proteinuria (P<0.05); Multivariate Logistic analysis showed that the course of disease, fasting blood glucose, blood pressure level, proteinuria, etc. were risk factors for diabetic lower extremity arterial disease.Conclusion Diabetic patients with vascular disease of the lower extremities had a longer course of diabetes, poor control of fasting blood sugar and blood pressure, and often had proteinuria.Attention should be paid to the above factors in clinical practice to control and improve the occurrence and development of diabetic lower limb vascular disease.

参考文献/References:

[1]孙子林,陆军,徐治,等.糖尿病足基层筛查与防治专家共识[J].中国糖尿病杂志,2019,27(6):401-407.[2]Ibrahim A.IDF Clinical Practice Recommendation on the Diabetic Foot:A guide for healthcare professionals[J].Diabetes research and clinical practice,2017(127):285-287.[3]许景灿,王娅平,陈燕,等.基于多中心的中国糖尿病足患者临床资料分析[J].中南大学学报(医学版),2019,44(8):898-904.[4]许建萍,肖新华,冯宝玉.2型糖尿病合并下肢动脉闭塞症危险因素分析[J].医学研究杂志,2020,49(3):35-38.[5]徐瑛,苏恒.2型糖尿病患者下肢动脉粥样硬化病变的相关危险因素分析与早期筛查[J].实用糖尿病杂志,2019,15(6):14-15.[6]陈静娴,叶山东,陈若平,等.2型糖尿病患者下肢动脉病变的相关因素分析[J].中国糖尿病杂志,2016,24(8):697-700.[7]杨敏,邓辉胜.高龄2型糖尿病患者下肢动脉硬化闭塞症的危险因素研究[J].中国全科医学,2017,20(1):71-75.[8]余宏建,郭学军,陈在中,等.糖尿病足下肢动脉病变的CTA及MRA影像特点及危险因素分析[J].中国CT和MRI杂志,2017,15(3):122-124.[9]孙顶双,丁肃,邢媛媛.老年2型糖尿病患者糖尿病足危险因素分析及常见感染菌[J].中国老年学杂志,2016,36(19):4769-4770.[10]魏金婴,王丹丹,张强,等.老年2型糖尿病患者下肢动脉硬化的危险因素分析[J].广东医学,2018,39(S1):157-159.[11]白慧华,周铸,邓楠.2型糖尿病患者发生血管并发症的危险因素分析[J].海南医学,2018,29(13):1802-1804.[12]徐波,杨彩哲,吴石白,等.糖尿病足患者截肢相关危险因素分析[J].中华内科杂志,2017,56(1):24-28.[13]熊朝月,唐祝奇,顾海云.糖尿病足患者发病、愈合、复发及风险因素[J].中国老年学杂志,2019,39(13):3121-3123.[14]张彬号,王瑞琼.吸烟对2型糖尿病患者动脉硬化的影响[J].深圳中西医结合杂志,2016,26(19):142-143.[15]杨毅,冉兴无.2型糖尿病患者下肢血管病变与蛋白尿的相关性研究[J].中国糖尿病杂志,2016,24(12):1065-1068.[16]中国医疗保健国际交流促进会糖尿病足病分会.中国糖尿病足诊治指南[J].中华医学杂志,2017,97(4):251-258.[17]黄强,王剑锋,翟仁友,等.无创影像检查方法诊断糖尿病下肢动脉病变的价值[J].中华放射学杂志,2015,49(1):20-24.[18]潘哲.彩色多普勒超声在糖尿病患者下肢血管病变诊断中的应用[J].糖尿病新世界,2019,22(23):28-29.[19]刘雪梅,何峥,吴凡,等.超声对糖尿病性下肢动脉狭窄及闭塞病变评估及相关危险因素的分析[J].中国实验诊断学,2019,23(1):94-96.[20]金成吉,唐田,于晓静,等.高糖及高胰岛素对人血管平滑肌细胞增殖、迁移及miR-145水平的影响[J].基础医学与临床,2017,37(1):94-97.[21]曹平良.探讨高血糖患者降压治疗的获益来源:从血压达标到血管保护[J].中华高血压杂志,2020,28(1):15-18.[22]李晓华,谢璇,戴信刚,等.2型糖尿病患者微量白蛋白尿与血管内皮功能关系的探讨[J].西安交通大学学报(医学版),2002(3):283-285,305.

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更新日期/Last Update: 1900-01-01