[1]杨 松.CT引导下多种微创技术联合治疗肺癌的有效性及安全性[J].医学信息,2021,34(12):139-141.[doi:10.3969/j.issn.1006-1959.2021.12.037]
　YANG Song.The Effectiveness and Safety of Multiple Minimally Invasive Techniques in the Treatment of Lung Cancer Under CT Guidance[J].Medical Information,2021,34(12):139-141.[doi:10.3969/j.issn.1006-1959.2021.12.037]
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CT引导下多种微创技术联合治疗肺癌的有效性及安全性()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年12期
页码:
139-141
栏目:
临床研究
出版日期:
2021-06-15

文章信息/Info

Title:
The Effectiveness and Safety of Multiple Minimally Invasive Techniques in the Treatment of Lung Cancer Under CT Guidance
文章编号:
1006-1959（2021）12-0139-03
作者:
杨 松
（朝阳县中心医院介入科，辽宁 朝阳 122000）
Author(s):
YANG Song
(Department of Intervention,Chaoyang Central Hospital,Chaoyang 122000,Liaoning,China)
关键词:
肺癌; 化学消融; 放射性粒子植入; 免疫功能
Keywords:
Lung cancer; Chemical ablation; Radioactive seed implantation; Immune function
分类号:
R734.2
DOI:
10.3969/j.issn.1006-1959.2021.12.037
文献标志码:
A
摘要:
目的 观察CT引导下多种微创技术联合治疗肺癌的有效性和安全性。方法 选取2018年1月~2020年1月我院诊治的76例肺癌患者为研究对象，采用随机数字表法分为对照组和观察组，各38例。对照组采用物理消融手术治疗，观察组在对照组基础上联合应用化学消融或放射性粒子植入治疗，比较两组治疗总有效率、肿瘤直径、中位生存期、免疫功能指标、并发症发生率。结果 观察组治疗总有效率为86.84%，高于对照组的76.31%，差异有统计学意义（P＜0.05）；观察组肿瘤直径小于对照组，差异有统计学意义（P＜0.05）；观察组中位生存期大于对照组，差异有统计学意义（P＜0.05）；治疗后两组CD3+、CD4+、CD4+/CD8+均较治疗前降低（P＜0.05），但组间比较，差异无统计学意义（P＞0.05）；观察组并发症发生率为28.94%，与对照组的31.57%比较，差异无统计学意义（P＞0.05）。结论 CT引导下多种微创技术联合治疗肺癌效果确切，可提高总有效率，缩小肿瘤直径，增加患者生存时间，对免疫功能影响较小，且不会增加并发症，具有较理想的有效性和安全性。
Abstract:
Objective To observe the effectiveness and safety of multiple minimally invasive techniques in the treatment of lung cancer under the guidance of CT.Methods A total of 76 lung cancer patients diagnosed and treated in our hospital from January 2018 to January 2020 were selected as the research objects, and were divided into the control group and the observation group by random number table method, with 38 cases in each group.The control group was treated with physical ablation surgery, and the observation group was treated with chemical ablation or radioactive seed implantation on the basis of the control group.The total effective rate of treatment, tumor diameter, median survival time, immune function indexes, and complication rate were compared between the two groups.Results The total effective rate of treatment in the observation group was 86.84%, which was higher than 76.31% in the control group,the difference was statistically significant(P<0.05);The diameter of the tumor in the observation group was smaller than that in the control group,the difference was statistically significant (P＜0.05);The median survival time of the observation group was longer than that of the control group,the difference was statistically significant (P＜0.05);After treatment, CD3+, CD4+, CD4+/CD8+ in the two groups were all lower than before treatment (P＜0.05),However, the difference between the groups was not statistically significant (P>0.05);The incidence of complications in the observation group was 28.94%, which was not statistically significant compared with 31.57% in the control group (P>0.05).Conclusion CT-guided combination of multiple minimally invasive techniques in the treatment of lung cancer has a definite effect, which can increase the total effective rate, reduce the tumor diameter, increase the survival time of the patient, have a small impact on the immune function, and will not increase complications, and has ideal effectiveness and safety.

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更新日期/Last Update: 1900-01-01