[1]陈天源,孙文豪,杨 扬,等.基于数据挖掘的心衰临床医案数据解构研究[J].医学信息官方网站,2022,35(15):20-25.[doi:10.3969/j.issn.1006-1959.2022.15.004]
 CHEN Tian-yuan,SUN Wen-hao,YANG Yang,et al.Data Deconstruction of Clinical Medical Records of Heart Failure Based on Data Mining[J].Medical Information,2022,35(15):20-25.[doi:10.3969/j.issn.1006-1959.2022.15.004]
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基于数据挖掘的心衰临床医案数据解构研究()
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《医学信息》官方网站[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年15期
页码:
20-25
栏目:
医学数据科学
出版日期:
2022-08-01

文章信息/Info

Title:
Data Deconstruction of Clinical Medical Records of Heart Failure Based on Data Mining
文章编号:
1006-1959(2022)15-0020-06
作者:
陈天源孙文豪杨 扬
(1.南京中医药大学第一临床医学院,江苏 南京 210029;2.南京医中数据挖掘中心,江苏 南京 210029;3.南京中医药大学附属宿迁市中医院心血管内科,江苏 宿迁 223800)
Author(s):
CHEN Tian-yuanSUN Wen-haoYANG Yanget al.
(1.First School of Clinical Medicine,Nanjing University of Chinese Medicine,Nanjing 210029,Jiangsu,China; 2.Data Mining Center,Medchitec Co.Ltd.,Nanjing 210029,Jiangsu,China; 3.Internal Medicine-Cardiovascular Department,Suqian TCM Hospital,Nanjing University of Chinese Medicine,Suqian 223800,Jiangsu,China)
关键词:
心力衰竭临床医案数据挖掘辨证论治
Keywords:
Heart failureMedical recordData miningTherapy with syndrome differentiation
分类号:
R259
DOI:
10.3969/j.issn.1006-1959.2022.15.004
文献标志码:
A
摘要:
目的 通过对各中医临床专家的医案进行文本挖掘,形成医案解析,分析各中医临床专家治疗心衰的经验。方法 选择中国知网、维普中文期刊、万方数据知识服务平台为目标数据库,检索建库至2020年10月17日公开发表的中医临床治疗心力衰竭医案类论文,筛选后采用频数分析等数据挖掘方法,从症状、舌苔、脉象、病机、治法、方药配伍等方面对各中医临床专家治疗心衰的医案资料进行分析。结果 共纳入医案406则,患者406人次,971诊次,症状123种,舌象31种,脉象21种,病机56条,治法治则29种,药物348种。结论 中医临床专家辨治心衰时高频症状为水肿、胸闷等,高频舌象为苔白、质暗等,高频脉象为细、沉等,高频病机为心阳虚、气虚等,高频治法治则为益气、利水等,高频药物为茯苓、黄芪、丹参等。
Abstract:
Objective To analyze the experience of TCM clinical experts in the treatment of heart failure by text mining of medical records of TCM clinical experts.Methods CNKI, VIP Chinese journals and Wanfang data knowledge service platform were selected as the target databases, and the medical records of TCM clinical experts in the treatment of heart failure published from the establishment of the database to October 17, 2020 were retrieved. After screening, data mining methods such as frequency analysis were used to analyze the medical records of TCM clinical experts in the treatment of heart failure from the aspects of symptoms, tongue coating, pulse condition, pathogenesis, treatment methods and prescription compatibility.Result A total of 406 medical records were included, including 406 patients, 971 visits, 123 symptoms, 31 tongue manifestations, 21 pulse manifestations, 56 pathogenesis, 29 therapeutic principles and 348 drugs.Conclusion When TCM clinical experts distinguish heart failure, clinical high frequency symptoms are edema, chest tightness, the high frequency tongue image is moss white, dark, the high frequency pulse signs are thin and heavy, the high frequency pathogenesis is heart yang deficiency and qi deficiency, the high frequency treatment is invigorating qi and diuresis, and the high frequency drugs are poria coco, astragalus and salvia miltiorrhiza, etc.

参考文献/References:

[1]吴承玉,王天芳.中医诊断学第三版[M].上海:科学技术出版社,2018.[2]唐德才,高学敏,吴庆光,等.中药学[M].北京:人民卫生出版社,2016.[3]徐亮.名老中医医案数据预处理及挖掘方法探讨[D].济南:山东中医药大学,2016.[4]杨涛,陆明,朱垚.基于FP-Growth的中医药数据关联分析平台的设计和应用[J].时珍国医国药,2016,27(12):3050-3052.[5]肖晓霞.基于机器学习的中医临床症状数据元研究[D].长沙:湖南中医药大学,2018.[6]张仲景.金匮要略[M].北京:人民卫生出版社,2005:54[7]周仲瑛.读经典,谈感悟[J].南京中医药大学学报,2007(5):273-277.[8]金政,吴伟,皮建彬,等.国医大师邓铁涛辨治心力衰竭的经验[J].中国中西医结合杂志,2020(6):754-755. [9]谢盈彧,方子寒,李渊芳,等.国医大师阮士怡运用育心保脉理论辨治心力衰竭经验[J].中国中西医结合杂志,2020(11):1388-1391.[10]陈书存.雷忠义国医大师治疗心衰病经验[J].陕西中医药大学学报,2020,43(1):23-25,47.[11]刘春玲,朱嘉,唐蜀华.唐蜀华教授心衰辨治心法[J].中西医结合心血管病电子杂志,2017(19):4-5,7.[12]郑林龙,蒋剑平,翁思思.响应面法优化土茯苓多糖的提取工艺及抗氧化活性研究[C]//“新成果·新进展·新突破”中华中医药学会2013年学术年会.2013:586.[13]郭毓菲,张诗泉,王汉迪,等.超声波法提取水溶性茯苓多糖工艺优化及其抗氧化活性探究[J].中国酿造,2018,37(12):160-164.[14]杨萍,周玉平,夏晴,等.HO-1介导黄芪甲苷抗原代心肌细胞缺氧/复氧损伤作用研究[J].天津中医药,2019,36(1):79-82.[15]陈广琴,何金龙,曲楠,等.AMPK/p38 MAPK通路介导黄芪多糖抑制大鼠心肌肥厚的研究[J].广西医科大学学报,2020,37(6):1018-1023.[16]曹亮,刘建华,冯平,等.黄芪多糖通过TLR4/NF-κB通路抑制COPD大鼠炎性反应诱导的平均血小板体积降低[J].疑难病杂志,2020,19(7):723-729.[17]张继红,覃慧林,贺海波,等.丹参对心衰大鼠心肌保护作用及SIRT1和SDF-1、CXCR4关系研究[J].中药药理与临床,2014,30(6):96-101.[18]王杰,贾连群,宋囡,等.四君子汤通过铁死亡途径改善动脉粥样硬化小鼠肝脏脂质沉积[J].解剖科学进展,2021(1):75-78.[19]李烨,王保和,徐强,等.生脉饮对慢性心力衰竭大鼠心功能及血清游离脂肪酸的影响[J].河南中医,2017,37(10):1732-1734.[20]黄贤娜,黄玲,罗洪波.基于TGF-β1/Smads通路研究补阳还五汤对心衰大鼠心肌重塑的干预作用[J].中药药理与临床,2019,35(5):15-20.[21]李洁白,袁慧婵,赵静,等.补阳还五汤对心衰大鼠肠道菌群及TMAO的影响[J].世界中西医结合杂志,2020(10):1814-1818.[22]伍燕宏,郑景辉,朱梓铭,等.真武汤治疗慢性心力衰竭的网络药理学机制研究[J].广州中医药大学学报,2019,36(10):1617-1623.[23]朱梓铭,张因彪,郑景辉,等.基于网络药理学探究苓桂术甘汤治疗慢性心力衰竭的作用机制[J].临床心血管病杂志,2019,35(2):154-161.

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更新日期/Last Update: 1900-01-01