[1]潘思佳,杨 鹏.以黄芪为君药的方药对2型糖尿病胰岛素抵抗影响的Meta分析[J].医学信息,2021,34(10):75-77.[doi:10.3969/j.issn.1006-1959.2021.10.021]
　PAN Si-jia,YANG Peng.Meta-analysis of the Influence of Astragalus-based Prescriptions on Insulin Resistance in Type 2 Diabetes[J].Medical Information,2021,34(10):75-77.[doi:10.3969/j.issn.1006-1959.2021.10.021]
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以黄芪为君药的方药对2型糖尿病胰岛素抵抗影响的Meta分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年10期
页码:
75-77
栏目:
论著
出版日期:
2021-05-15

文章信息/Info

Title:
Meta-analysis of the Influence of Astragalus-based Prescriptions on Insulin Resistance in Type 2 Diabetes
文章编号:
1006-1959（2021）10-0075-04
作者:
潘思佳; 杨 鹏
（贵州中医药大学第二附属医院检验科，贵州 贵阳 558003）
Author(s):
PAN Si-jia; YANG Peng
(Department of Laboratory Medicine,the Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang 558003,Guizhou,China)
关键词:
2型糖尿病; 黄芪; 胰岛素抵抗指数
Keywords:
Type 2 diabetes; Astragalus; Insulin resistance index
分类号:
R587.1
DOI:
10.3969/j.issn.1006-1959.2021.10.021
文献标志码:
A
摘要:
目的 系统评价以黄芪为君药的方药对糖尿病胰岛素抵抗的影响。方法 从中国知网，维普及万方数据库检索以黄芪为君药的方药治疗糖尿病的相关文献，检索年限截止2020年1月，以胰岛素抵抗指数为评价指标，运用RevMan5.3软件进行Meta分析。结果 共纳入文献7篇，治疗组334例，对照组293例。Meta分析显示，治疗组胰岛素抵抗指数低于对照组（P＜0.05）。进一步以方药的功效进行亚组分析显示，黄芪单方及黄芪+滋阴益气对胰岛素抵抗指数无影响（P＞0.05），但黄芪+温阳健脾方药可下调胰岛素抵抗指数（P＜0.05）。结论 以黄芪为君药的方药联合二甲双胍治疗可改善2型糖尿病胰岛素抵抗，特别是黄芪+温阳健脾的方药疗效更为显著。
Abstract:
Objective To systematically evaluate the effects of astragalus-based prescriptions on insulin resistance in diabetes.Methods From CNKI,the Weipu Wanfang database was used to retrieve relevant literature on the treatment of diabetes with astragalus-based prescriptions. The search period was as of January 2020. The insulin resistance index was used as the evaluation index, and the RevMan5.3 software was used for Meta analysis.Results A total of 7 articles were included, with 334 cases in the treatment group and 293 cases in the control group. Meta analysis showed that the insulin resistance index of the treatment group was lower than that of the control group (P<0.05).Further subgroup analysis based on the efficacy of the prescriptions showed that astragalus single prescription and astragalus + nourishing yin and nourishing qi had no effect on the insulin resistance index (P>0.05).But Astragalus+Wenyang Jianpi prescription can down-regulate the insulin resistance index (P<0.05).Conclusion Astragalus-based prescriptions combined with metformin treatment can improve insulin resistance in type 2 diabetes, especially the prescription of Astragalus plus Wenyang Jianpi has a more significant effect.

参考文献/References:

[1]罗爱彬.二甲双胍在改善2型糖尿病胰岛素抵抗中应用观察[J].当代医学,2016,22(2):146-147.[2]肖小惠,李惠林,刘德亮,等.活血降糖饮联合二甲双胍对2型糖尿病胰岛素抵抗患者糖脂代谢及脂肪因子的影响[J].广州中医药大学学报,2015(5):799-802.[3]陈晓,周晓春,金艺璇,等.黄芪联合二甲双胍对初诊2型糖尿病患者胰岛素抵抗及血浆胰淀素水平的影响[J].国际中医中药杂志,2014,36(2):114-116.[4]阮永队,陈红梅,莫冰泉,等.中医温阳健脾法与降糖药合用治疗2型糖尿病胰岛素抵抗阳虚患者70例[J].广州中医药大学学报,2007(3):184-187.[5]李蓉,张春蓉,陈坤.健脾益气类中医治疗2型糖尿病胰岛素抵抗40例[J].陕西中医,2011,32(7):866-868.[6]陈小广.西药联合黄芪葛根汤治疗糖尿病36例疗效观察[J].中国民族民间医药,2019(15):68-70.[7]黄春玲,吕玉萍.黄芪辅助治疗2型糖尿病对胰岛素抵抗的影响[J].中国中西医结合杂志,2003(10):779-780.[8] 张景祖. 温阳健脾汤联合二甲双胍治疗2型糖尿病(脾肾阳虚)随机平行对照研究 [J].实用中医内科杂志,2017,31(10):32-34.[9]龚全友,侯芳丽,刘华,等.2型糖尿病及前期患者血脂水平变化及其与胰岛素抵抗的关系[J].中国执业药师,2019,16(5):37-40.[10]李华峰,张广凤,赵文杰,等.2型糖尿病内脏脂肪含量与胰岛β细胞功能及胰岛素抵抗的关系研究[J].现代生物医学进展,2019,19(14):150-152,169.[11]张之弘,杨丽霞,孟祥云,等.基于数据挖掘分析当归治疗糖尿病的研究现状[J].西部中医药,2019,32(4):74-78.[12]李杏英,张松林,袁学进,等.中药饮片黄芪对2型糖尿病胰岛分泌功能和胰岛素抵抗的影响[J].中国医药科学,2012(14):85-85,104.

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更新日期/Last Update: 1900-01-01