[1]纪东华.托伐普坦治疗AMI合并心力衰竭的疗效及对患者血清hs-CRP、NT-proBNP表达的影响[J].医学信息,2019,32(16):127-128.[doi:10.3969/j.issn.1006-1959.2019.16.041]
 JI Dong-hua.Efficacy of Tolvaptan in the Treatment of AMI Complicated with Heart Failure and its Effect on Serum hs-CRP and NT-proBNP Expression[J].Journal of Medical Information,2019,32(16):127-128.[doi:10.3969/j.issn.1006-1959.2019.16.041]
点击复制

托伐普坦治疗AMI合并心力衰竭的疗效及对患者血清hs-CRP、NT-proBNP表达的影响()
分享到:

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年16期
页码:
127-128
栏目:
药物与临床
出版日期:
2019-08-15

文章信息/Info

Title:
Efficacy of Tolvaptan in the Treatment of AMI Complicated with Heart Failure and its Effect on Serum hs-CRP and NT-proBNP Expression
文章编号:
1006-1959(2019)16-0127-02
作者:
纪东华
佳木斯市中心医院心内科,黑龙江 佳木斯 154002
Author(s):
JI Dong-hua
Department of Cardiology,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China
关键词:
急性心肌梗死心力衰竭托伐普坦hs-CRPNT-proBNP
Keywords:
Key words:Acute myocardial infarctionHeart failureTolvaptanhs-CRPNT-proBNP
分类号:
R541.6;R542.2
DOI:
10.3969/j.issn.1006-1959.2019.16.041
文献标志码:
A
摘要:
目的 探讨托伐普坦治疗急性心肌梗死(AMI)合并心力衰竭的疗效及对患者血清hs-CRP、NT-proBNP表达的影响。方法 选取我院2016年8月~2018年9月收治的AMI合并心力衰竭患者84例,按随机数字表法分为对照组和观察组,各42例。对照组常规予以急救治疗与抗心衰药物治疗,观察组同时联合托伐普坦治疗,比较两组疗效及血清hs-CRP、NT-proBNP水平。结果 观察组总有效率为95.24%,高于对照组的78.57%(P<0.05)。治疗1周后,观察组血清hs-CRP、NT-proBNP水平均低于对照组(P<0.05)。结论 托伐普坦治疗急性心肌梗死合并心力衰竭有助于提高疗效,改善血清hs-CRP、NT-proBNP指标。
Abstract:
Abstract:Objective To investigate the effect of tolvaptan on acute myocardial infarction (AMI) complicated with heart failure and its effect on serum hs-CRP and NT-proBNP expression. Methods 84 patients with AMI complicated with heart failure admitted to our hospital from August 2016 to September 2018 were enrolled. The patients were divided into the control group and the observation group according to the random number table, 42 cases each. The control group was routinely treated with emergency treatment and anti-heart failure medication. The observation group was treated with tolvaptan at the same time. The efficacy and serum hs-CRP and NT-proBNP levels were compared between the two groups. Results The total effective rate of the observation group was 95.24%, which was higher than that of the control group 78.57%(P<0.05). After 1 week of treatment, the serum hs-CRP and NT-proBNP levels in the observation group were lower than those in the control group(P<0.05).Conclusion Tolvaptan in the treatment of acute myocardial infarction complicated with heart failure can improve the efficacy and improve serum hs-CRP and NT-proBNP.

参考文献/References:

[1]徐宝华,赵刚.托伐普坦治疗急性心肌梗死合并心力衰竭的疗效及对心肾功能的影响[J].中国老年学杂志,2018,38(15):46-48. [2]王茜,杨小东,刘东霞,等.托伐普坦与托拉塞米治疗重症心力衰竭伴稀释性低钠血症的效果比较[J].河北医药,2018,40(23):3582-3584. [3]魏立侠,张英杰,翟桂兰.托伐普坦治疗顽固性心力衰竭的疗效研究[J].中国循环杂志,2016,31(4):341-344. [4]隋利军,李维,甘建祥,等.托伐普坦对慢性心力衰竭急性发作合并利尿剂抵抗的疗效研究[J].国际心血管病杂志,2018,45(3):62-64. [5]刘泉.托伐普坦治疗心力衰竭的疗效及其对患者心肾功能的影响[J].中国现代药物应用,2016,10(7):119-120.

相似文献/References:

[1]郭俊林,张立.BNP对CRT后期疗效的临床评价[J].医学信息,2018,31(01):67.[doi:10.3969/j.issn.1006-1959.2018.01.024]
 GUO Jun-lin,ZHANG li.Clinical Evaluation of BNP in Treatment of Late CRT[J].Journal of Medical Information,2018,31(16):67.[doi:10.3969/j.issn.1006-1959.2018.01.024]
[2]郭建华.丹参川芎嗪联合阿托伐他汀钙治疗急性心肌梗死的疗效观察[J].医学信息,2018,31(01):145.[doi:10.3969/j.issn.1006-1959.2018.01.056]
 GUO Jian-hua.Effect of Salvia Miltiorrhiza Tetramethylpyrazine Combined with Atorvastatin Calcium in the Treatment of Acute Myocardial Infarction[J].Journal of Medical Information,2018,31(16):145.[doi:10.3969/j.issn.1006-1959.2018.01.056]
[3]余湘宁,赵献明.ECMO在危重症心脏疾病中的应用研究[J].医学信息,2018,31(04):38.[doi:10.3969/j.issn.1006-1959.2018.04.013]
 YU Xiang-ning,ZHAO Xian-ming.Study on the Application of ECMO in Critical Heart Disease[J].Journal of Medical Information,2018,31(16):38.[doi:10.3969/j.issn.1006-1959.2018.04.013]
[4]程 林.重组人脑利钠肽用于重症急性心肌炎伴 心力衰竭患者治疗的临床研究[J].医学信息,2018,31(08):126.[doi:10.3969/j.issn.1006-1959.2018.08.042]
 CHENG Lin.Clinical Study of Recombinant Human Brain Natriuretic Peptide in the Treatment of Patients with Severe Acute Myocarditis and Heart Failure[J].Journal of Medical Information,2018,31(16):126.[doi:10.3969/j.issn.1006-1959.2018.08.042]
[5]胡丽君.螺内酯联合曲美他嗪治疗慢性心力衰竭的疗效分析[J].医学信息,2018,31(08):131.[doi:10.3969/j.issn.1006-1959.2018.08.044]
 HU Li-jun.Efficacy of Spironolactone Combined with Trimetazidine in the Treatment of Chronic Heart Failure[J].Journal of Medical Information,2018,31(16):131.[doi:10.3969/j.issn.1006-1959.2018.08.044]
[6]李 铎,王建华.盐酸曲美他嗪片辅助治疗对冠心病伴心力衰竭患者氧化应激、心肌功能的影响[J].医学信息,2018,31(10):126.[doi:10.3969/j.issn.1006-1959.2018.10.041]
 LI Duo,WANG Jian-hua.Effect of Trimetazidine Hydrochloride Tablets Adjuvant Therapy on Oxidative Stress and Myocardial Function in Patients with Coronary Heart Disease Complicated with Heart Failure[J].Journal of Medical Information,2018,31(16):126.[doi:10.3969/j.issn.1006-1959.2018.10.041]
[7]平兰芝,黄小楼,胡天俊,等.CaMKⅡ在心血管疾病中的研究[J].医学信息,2022,35(10):59.[doi:10.3969/j.issn.1006-1959.2022.10.014]
 PING Lan-zhi,HUANG Xiao-lou,HU Tian-jun,et al.Research on the Role of CaMKⅡ in Cardiovascular Diseases[J].Journal of Medical Information,2022,35(16):59.[doi:10.3969/j.issn.1006-1959.2022.10.014]
[8]何 丽.应激性高血糖与急性心肌梗死的机制研究[J].医学信息,2022,35(10):74.[doi:10.3969/j.issn.1006-1959.2022.10.018]
 HE Li.Mechanism of Stress Hyperglycemia and Acute Myocardial Infarction[J].Journal of Medical Information,2022,35(16):74.[doi:10.3969/j.issn.1006-1959.2022.10.018]
[9]毛红岩,宁国贤.冠脉介入治疗对冠心病急性心肌梗死患者 心肌损伤及心室重塑的影响[J].医学信息,2018,31(12):102.[doi:10.3969/j.issn.1006-1959.2018.12.031]
 MAO Hong-yan,NING Guo-xian.Effects of Coronary Intervention on Myocardial Injury and Ventricular Remodeling in Patients with Coronary Heart Disease and Acute Myocardial Infarction[J].Journal of Medical Information,2018,31(16):102.[doi:10.3969/j.issn.1006-1959.2018.12.031]
[10]刘革铭,马洪俊,刘 毅,等.心力衰竭的机制及诊疗的研究[J].医学信息,2022,35(10):91.[doi:10.3969/j.issn.1006-1959.2022.10.022]
 LIU Ge-ming,MA Hong-jun,LIU Yi,et al.Mechanism, Diagnosis and Treatment of Heart Failure[J].Journal of Medical Information,2022,35(16):91.[doi:10.3969/j.issn.1006-1959.2022.10.022]
[11]马洪俊,王玉平,刘 毅.主动脉内球囊反搏联合介入治疗急性心肌梗死伴心力衰竭的效果[J].医学信息,2022,35(13):136.[doi:10.3969/j.issn.1006-1959.2022.13.032]
 MA Hong-jun,WANG Yu-ping,LIU Yi.Effect of Intra-aortic Balloon Counterpulsation Combined with Interventional Therapy on Acute Myocardial Infarction Complicated with Heart Failure[J].Journal of Medical Information,2022,35(16):136.[doi:10.3969/j.issn.1006-1959.2022.13.032]

更新日期/Last Update: 2019-08-15